Antibody and Protein Sequencing Services
Our antibody sequencing services can determine the amino acid sequence of monoclonal or polyclonal antibodies with our proprietary high-throughput, full coverage de novo antibody sequencing technology.
- Established Antibody Sequencing Platform
Our REmAb® and REpAb® solutions are built on a strong foundation of over 20 years of mass spectrometry and bioinformatics expertise. We foster continuous innovation. Our patented protein chemistry protocols and proprietary big data machine learning algorithms facilitate novel discoveries, empowering our clients to further their research faster and more confidently.
- High-Throughput, Uncompromisingly Accurate
REmAb®’s core strength is its uncompromising accuracy. Thousands of overlapping peptides support the protein sequence, which is why we can confidently claim 100% accuracy. REmAb®’s fast and robust platform fuels trailblazing research worldwide.
- Enabling and Safeguarding Discoveries
A consistently reliable antibody is one of a kind. With REmAb® and REpAb®, researchers have the choice to use mAbs and pAbs without being blind to protein sequence information – thereby safeguarding results for project continuance, patents, regulatory approvals, and antibody production
REmAb® Monoclonal Antibody Sequencing
How It Works
The REmAb® workflow delivers a full coverage antibody sequence with unparalleled accuracy, 100% of the time (see sample requirements below). Starting with only a small sample of protein, we conduct proprietary chemistry, LC-MS/MS proteomics and machine-learning driven sequencing.
Turn-around time
- 11+ samples, 4 weeks
- 2-10 samples, 3 weeks
- 1 sample, 2 weeks
- Rush, 1 week
Requirements
- Any species
- Any antibody isotype
- 100 μg of protein, >80% purity
- Is your sample smaller or less pure?
- Ask us. We can often still get results.
Deliverables
- The entire mAb sequence averaging 30X coverage per amino acid. Sample coverage view.
- Independent review – sequences derived by proprietary bioinformatics and expert reviews.
- Isobaric checks – all isobaric combinations are determined by WILD®.
Non-ab Protein Sequencing Service that Drives Innovation
Our de novo protein sequencing service resolves the exact amino acid sequence of your purified protein. Based on proprietary mass spectrometry and bioinformatics technology, your complete sequence analysis is delivered in as little as 1 week.
- Next Generation Protein Sequencing
Our scientists have been developing de novo protein sequencing for the past 20 years. Patented chemistry, tight integration between our mass spectrometry and bioinformatics teams, and proprietary algorithms have advanced de novo protein sequencing to the next generation: REmAb. This means fast, reliable and complete protein sequencing, and countless breakthroughs for our clients.
- Accurate Sequence Results at Scale
REmAb® protein sequencing is built for uncompromising accuracy. Thousands of overlapping de novo peptide sequences and automated protein sequence assembly support the protein sequence and deliver 100% accuracy. Proceed with confidence.
Peptide Mapping & Analysis
Reduce Risk and Avoid Delays with Rapid Peptide Mapping Service.
MATCHmAb™ peptide mapping service is a routine, fast and easy solution to verify your antibodies, reduce risk and increase reproducibility at every step of your workflow. Our proprietary MATCHmAb™ technology analyzes and confirms that the sequence of your produced or procured antibody matches the expected sequence, and can identify anomalies for further study.
Benefits of Rapid Peptide Mapping
- Reduce risk of failure or wasted time – verify early and often to prevent downstream issues
- Fast answers – answers in days, not weeks
- Go high-throughput – hundreds of samples per week in our purpose built protein sequencing facility
- Cost effective – make it part of your routine
- Easy to use – subscription plan or bulk order make it easy for your team
- Avoid troubleshooting – a simple first step to avoid re-running work
- Quality control – check every batch, fast and easy
- IP Protection – confirm the unique sequence of your antibody
How It Works: The Evolution of Peptide Mapping & Analysis
| MATCHmAb™ | Traditional Peptide Mapping | |
|---|---|---|
| Workflow | LC-MS/MS, single or dual digest | LC-MS only, single enzyme only |
| Bioinformatics | Real-time analysis, purpose built algorithms | Post-processing, off the shelf tools |
| Speed | Fast: 1-4 days | Slow: weeks |
| Throughput | High: > 100 per week | Low |
| Coverage | Higher, and amino acid level | Lower, and only peptide level |
Contact us for more information
Download the Buyers Guide for further information.
