Webinar: Nuclear Receptors and Drug-Drug Interactions
Nuclear Receptors and Drug-Drug Interactions: How to Better Understand Potential Toxicity
Learn about various drug screening assays that are available for identifying potential DDI in vitro.
Online
Register for this webinar to learn about various drug screening assays that are available for identifying potential DDI in vitro. Drug screening assays improve drug safety and allow for the prioritization of drug candidates. PXR and several other important xenobiotic sensing and drug metabolism inducing systems will be described. These include Aryl hydrocarbon receptor (AhR), constitutive androstane receptor (CAR), Farnesoid X Receptor (FXR) and Nuclear factor-erythroid factor 2-related factor 2 (Nrf2).
The featured speaker will also discuss how in vitro assays can be used for species extrapolation of pharmacokinetic interactions for common laboratory animal models. These in vitro assays save time and money lost from pursuing candidates that may fail in animal or clinical trials.
Speaker: Jack Vanden Heuvel, Professor of Molecular Toxicology, Pharmacology - Penn State University; CSO, INDIGO Biosciences
When: Friday, April 29, 2022 at 19:00 CET
Where: Online (free)