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New TP53INP2 & GABARAP Antibodies
TP53INP2 antibody (catalog# NBP1-71704) & GABARAP antibody (catalog# NBP1-71771)
Novus Biologicals announced new antibodies to TP53INP2 (NBP1-71704) and GABARAP
(NBP1-71771) for use in autophagy research.
Tumor Protein 53-Induced Nuclear Protein 2 (TP53INP2) is thought to be a scaffold protein which translocates from the nucleus to autophagosomes during preparation for autophagy. TP53INP2 binds LC3-related proteins, including GABARAP and VMP1. Research has shown that both TP53INP2 and GABARAP are required for autophagy in mammalian cells.
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Immunofluorescence analysis of TP53INP2 in HeLa cells using NBP1-71704 at 1:200 with a FITC secondary (green). Nuclei and actin were counterstained with Dapi (blue) and Phalloidin (red).
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Immunohistochemistry analysis of TP53INP2 in mouse prostate using NBP1-71704.
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Immunohistochemistry analysis of GABARAP in mouse liver using NBP1-71771.
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Immunofluorescence analysis of GABARAP in HeLa cells using NBP1-71771 at 1:200 with a FITC secondary (green). Nuclei and actin were counterstained with Dapi (blue) and Phalloidin (red).
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These new antibodies have been validated for use in immunofluorescence staining on human and mouse samples. However, we also offer an Innovator’s Reward™ Program for testing in novel species and applications.
TP53INP2 in the News:
1. Nowak J, Archange C, Tardivel-Lacombe J, et al. The TP53INP2 protein is required for autophagy in mammalian cells. MolBiol Cell. 2009 Feb;20(3):870-81. [PMID: 19056683].
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