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In This Issue
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AAV Helper Free Systems
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TECH CORNER: ViraBind AAV Purification Kit
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Measuring AAV Titer
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AAV Purification
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Increase Transduction Efficiency
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New 2012-2013 Catalog will contain many new cutting-edge products.
Pre-order your copy: info@lubio.ch
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Other Cell Biolabs Product Lines
Cell-Based Assays
Cell Signaling & Protein Biology
Infectious Disease Research
Metabolism Research
miRNA Analysis
Oxidative Stress/Damage
Stem Cell Research
Viral Expression
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Recombinant AAV has become a useful tool for gene delivery into a wide variety of target cells, because it can transduce non-dividing cells and generates an extremely low immune response.
Read on to find out how our broad selection of AAV kits and reagents can improve your gene expression studies.
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AAV Helper Free Systems Increase Infectivity
The AAV Helper Free System was developed to make production of AAV safer 
and more convenient. We have expanded the AAV Helper Free System to create the broadest portfolio of AAV expression systems.
Our AAV Helper Free Systems are available in the following formats:
- AAV native serotypes 1 through 6
- AAV-DJ, engineered by DNA family shuffling to create a hybrid capsid from 8 AAV serotypes; the resulting vector conveys significantly higher infectivity rates compared to native AAV across a broad range of cells and tissue types
- AAV-DJ/8, a mutant of AAV-DJ that exhibits increased uptake in brain tissue in vivo, similar to AAV-8 and AAV-9
- Each Helper Free Expression System includes your choice of 7 different expression vectors including our newest AAV promoterless vector
For more information please contact us
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Measure AAV Titer Quickly and Easily
 Quantitation of AAV has traditionally been done by DNA dot blots, which can be time-consuming and suffer from high inter-assay variability. Our QuickTiter™ AAV Quantitation Kit quantifies the nucleic acid from AAV particles in less than two hours. The kit uses proprietary technology to quantify unpurified AAV-2 or AAV-DJ supernatant and purified AAV of any serotype.
For more information please contact us
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Purify AAV Without an Ultracentrifuge!
Ultracentrifugation is a tedious, time-consuming way to concentrate
AAV, and it only provides partial purification.
Our ViraBind™ AAV Purification Kits can purify your AAV-2 or AAV-DJ preps without the use of an ultracentrifuge.
For more information please contact us
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Maximize AAV Transduction Efficiency
AAV infection of your target cell involves a rate-limiting second-strand synthesis step, which can limit transduction efficiencies leading to poor gene expression.
The ViraDuctin™ AAV Transduction Kit is a multi-reagent formulation that can increase transduction efficiency of AAV vectors.
For more information please contact us: info@lubio.ch
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