Featured RUNX2 Antibody

RUNX2 Antibodies (catalog# NBP1-77461 & NBP1-77462)

Novus Biologicals announced today two new RUNX2 Antibodies (NBP1-77461 & NBP1-77462) for use in research on osteoblast differentiation and bone formation.

Runt-related transcription factor 2 (RUNX2) is a transcription factor important for osteoblast differentiation and maturation, as well as skeletal morphogenesis. Novus’ new RUNX2 Antibodies (NBP1-77461 & NBP1-77462) have been validated for use in immunofluorescence staining of human and mouse samples. However, we also offer an Innovator’s Reward™ Program for testing in novel species and applications.

IF Image of RUNX2

IHC Image of RUNX2

Immunofluorescece staining of HeLa cells using RUNX2 Antibody (NBP1-77461) with a FITC (green) secondary.  Nuclei and actin were counterstained with Dapi (blue) and Phalloidin (red).

Immunohistochemistry staining of mouse prostate tissue using RUNX2 Antibody (NBP1-77462) with DAB visualization and a hematoxylin counterstain.

RUNX2 in the News:

1.     van der Deen M, Akech J, Lapointe D, et al. Genomic promoter occupancy of runt-related transcription factor RUNX2 in osteosarcoma cells identifies genes involved in cell adhesion and motility. J Biol Chem. 2011 Dec 9. [PMID: 22158627]

2.     Tu X, Joeng KS, Long F. Indian hedgehog requires additional effectors besides Runx2 to induce osteoblast differentiation. Dev Biol. 2011 Dec 2. [PMID: 22155527]

Novus also offers other RUNX2 antibodies, recombinant proteins and control lysates, as well as other ancillary reagents.